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| Catalog_no | ADMC0271 |
| Product_name | BKM120 (NVP-BKM120, Buparlisib) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1000.00/1340.00/1660.00 |
| Specificity | Target: PI3K. Fields: BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. |
| Dilution | IC50: 52 nM (p110α), 166 nM (p110β), 116 nM (p110δ), 262 nM (p110γ)[1] |
| Purification | >98% |
| Concentration | 靶点：PI3K;IC50： 52 nM (p110α), 166 nM (p110β), 116 nM (p110δ), 262 nM (p110γ)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | NVP-BKM-120, BKM-120; Buparlisib |
| Observed_band | 410.39 |
| Notes | BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. |
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