抑制剂与激动剂

Catalog_noADMC0313
Product_nameBi 2536
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price2200.00/5860.00/9520.00
SpecificityTarget: Polo-like Kinase (PLK). Fields: BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM).
DilutionIC50: 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1]IC50: 25 nM (BRD4)[2]
Purification>98%
Concentration靶点:Polo-like Kinase (PLK);IC50: 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1] 25 nM (BRD4)[2]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameBI-2536; BI2536
Observed_band521.66
NotesBI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM).
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