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Catalog_no | ADMC0313 |
Product_name | Bi 2536 |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 2200.00/5860.00/9520.00 |
Specificity | Target: Polo-like Kinase (PLK). Fields: BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
Dilution | IC50: 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1]IC50: 25 nM (BRD4)[2] |
Purification | >98% |
Concentration | 靶点:Polo-like Kinase (PLK);IC50: 0.83 nM (Plk1), 3.5 nM (Plk2/Snk), 9 nM (Plk3/Fnk)[1] 25 nM (BRD4)[2] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | BI-2536; BI2536 |
Observed_band | 521.66 |
Notes | BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). |
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