抑制剂与激动剂

Catalog_noADMC0334
Product_nameE7080 (Lenvatinib)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price780.00/1660.00/2660.00
SpecificityTargetTarget inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β.
DilutionIC50: 4 nM (VEGFR2), 5.2 nM (VEGFR3)
Purification>99%
Concentration靶点:VEGFR;IC50: 4 nM (VEGFR2), 5.2 nM (VEGFR3)
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameE7080; Vargatef; E-7080; E 7080
Observed_band426.85
NotesE7080 (Lenvatinib; Vargatef) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β.
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