400-921-8278
Catalog_no | ADMC0349 |
Product_name | Omipalisib(GSK-458) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 1780.00/4660.00/8400.00 |
Specificity | Target: PI3K. Fields: GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2 , respectively. Ki: 0.019 nM (p110α), 0.13 nM (p110β), 0.024 nM (p110δ), 0. |
Dilution | Ki: 0.019 nM (p110α), 0.13 nM (p110β), 0.024 nM (p110δ), 0.06 nM (p110γ), 0.18 nM (mTORC1), 0.3 nM (mTORC2) |
Purification | >98% |
Concentration | 靶点:PI3K;IC50:Ki: 0.019 nM (p110α), 0.13 nM (p110β), 0.024 nM (p110δ), 0.06 nM (p110γ), 0.18 nM (mTORC1), 0.3 nM (mTORC2) |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | GSK212; GSK-2126458; GSK 2126458; GSK-212; GSK 212,GSK458,GSK 458,GSK2126458 |
Observed_band | 505.5 |
Notes | GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2 , respectively. Ki: 0.019 nM (p110α), 0.13 nM (p110β), 0.024 nM (p110δ), 0.06 nM (p110γ), 0.18 nM |
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