400-921-8278
| Catalog_no | ADMC0364 |
| Product_name | AGI-6780 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1660.00/5560.00/10000.00 |
| Specificity | Target: Isocitrate Dehydrogenase (IDH). Fields: AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM). |
| Dilution | IC50: 23±1.7 nM (IDH2R140Q), 190±8.1 nM (IDH2WT)[1] |
| Purification | >98% |
| Concentration | 靶点：Isocitrate Dehydrogenase (IDH);IC50： 23±1.7 nM (IDH2R140Q), 190±8.1 nM (IDH2WT)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | AGI 6780; AGI6780 |
| Observed_band | 481.5 |
| Notes | AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM). |
| Instructions | 
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