400-921-8278
| Catalog_no | ADMC0376 |
| Product_name | LCL-161 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1780.00/5560.00/8220.00 |
| Specificity | Target: IAP. Fields: LCL161 is an oral small molecule antagonist of Apoptosis Proteins (IAPs) that sensitizes a subset of tumors from diverse lineages to treatment with cytotoxic therapies. IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA- |
| Dilution | IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1] |
| Purification | >98% |
| Concentration | 靶点：IAP;IC50： 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | LCL-161; LCL161 |
| Observed_band | 500.63 |
| Notes | LCL161 is an oral small molecule antagonist of Apoptosis Proteins (IAPs) that sensitizes a subset of tumors from diverse lineages to treatment with cytotoxic therapies. IC50: 35 nM (XIAP, in HEK293 cell), 0.40 nM (cIAP1, in MDA-MB-231)[1] |
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