| Catalog_no | ADMC0382 |
| Product_name | JAK Inhibitor I(merk 5) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 3000.00/8760.00/15560.00 |
| Specificity | Target: JAK. Fields: Merck 5 is a potent and reversible ATP-competitive inhibitor of the JAK kinases (JAK1, JAK2, JAK3, and Tyk2). It also blocks IL2 and IL4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5. IC50: 1 nM |
| Dilution | IC50: 1 nM (JAK2), 5 nM (JAK3), 15 nM (JAK1), 1 nM (TYK2)[1] |
| Purification | >98% |
| Concentration | 靶点：JAK;IC50： 1 nM (JAK2), 5 nM (JAK3), 15 nM (JAK1), 1 nM (TYK2)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | Merck 5,Merck5 |
| Observed_band | 309.3 |
| Notes | Merck 5 is a potent and reversible ATP-competitive inhibitor of the JAK kinases (JAK1, JAK2, JAK3, and Tyk2). It also blocks IL2 and IL4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5. IC50: 1 nM (JAK2), 5 nM (JAK3), |
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