抑制剂与激动剂

Catalog_noADMC0385
Product_nameMotesanib Diphosphate (AMG-706)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price560.00/1780.00/3120.00
SpecificityTarget: c-Kit. Fields: Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
Dilution
Purification>98%
Concentration靶点:c-Kit;IC50:No data
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameAMG706; AMG 706; AMG-706
Observed_band569.44
NotesMotesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
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