抑制剂与激动剂

Catalog_noADMC0405
Product_nameRepsox(ALK5 Inhibitor II)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price1000.00/3880.00/7000.00
SpecificityTarget: TGF-beta/Smad. Fields: RepSox(E-616452; SJN 2511) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation, respectively.
DilutionIC50: 4 nM (ALK5 autophosphorylation)[1]
Purification>98%
Concentration靶点:TGF-beta/Smad;IC50: 4 nM (ALK5 autophosphorylation)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameE-616452; SJN 2511; E616452; SJN2511; E 616452; SJN-2511
Observed_band287.32
NotesRepSox(E-616452; SJN 2511) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation, respectively.
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