400-921-8278
| Catalog_no | ADMC0440 |
| Product_name | TG101209 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1500.00/4500.00/8340.00 |
| Specificity | Target: FLT3. Fields: TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 a |
| Dilution | IC50: 6 nM (JAK2), 25 nM (Flt3), 17 nM (RET), 130 nM (BRD4) |
| Purification | >98% |
| Concentration | 靶点：FLT3;IC50： 6 nM (JAK2), 25 nM (Flt3), 17 nM (RET), 130 nM (BRD4) |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | TG 101209; TG-101209 |
| Observed_band | 509.67 |
| Notes | TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 activity with IC50 of 13 |
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