400-921-8278
| Catalog_no | ADMC0483 |
| Product_name | DAPT |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1060.00/3280.00/5920.00 |
| Specificity | Target: γ-secretase. Fields: DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, ce |
| Dilution | IC50: 20 nM (Aβ, in HEK 293 cells)[1] |
| Purification | >98% |
| Concentration | 靶点：γ-secretase;IC50： 20 nM (Aβ, in HEK 293 cells)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | GSI-IX; GSI IX |
| Observed_band | 432.46 |
| Notes | DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma. |
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