抑制剂与激动剂

Catalog_noADMC0507
Product_nameLDN193189 HCl
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price1000.00/2660.00/4800.00
SpecificityTarget: ALK. Fields: LDN193189 HCl is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
DilutionIC50: 5 nM (ALK2), 30 nM (ALK3)[1]
Purification>98%
Concentration靶点:ALK;IC50: 5 nM (ALK2), 30 nM (ALK3)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameLDN-193189 HCl,LDN 193189 HCl
Observed_band442.94
NotesLDN193189 HCl is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
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