抑制剂与激动剂

Catalog_noADMC0537
Product_nameVE-822
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price1140.00/3640.00/6120.00
SpecificityTarget: ATM/ATR . Fields: VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cel
DilutionKi: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
Purification>98%
Concentration靶点:ATM/ATR;IC50:Ki: <0.2 nM (ATR), 34 nM (ATM)[1] 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameVE822; VE 822
Observed_band463.55
NotesVE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1
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