| Catalog_no | ADMC0537 |
| Product_name | VE-822 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1140.00/3640.00/6120.00 |
| Specificity | Target: ATM/ATR . Fields: VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cel |
| Dilution | Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
|
| Purification | >98% |
| Concentration | 靶点：ATM/ATR;IC50：Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1]
|
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | VE822; VE 822 |
| Observed_band | 463.55 |
| Notes | VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1]
IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 |
| Instructions | 
查看与下载 |
| Share |
|
