400-921-8278
Catalog_no | ADMC0537 |
Product_name | VE-822 |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 1140.00/3640.00/6120.00 |
Specificity | Target: ATM/ATR . Fields: VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cel |
Dilution | Ki: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1] |
Purification | >98% |
Concentration | 靶点:ATM/ATR;IC50:Ki: <0.2 nM (ATR), 34 nM (ATM)[1] 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 and MiaPaCa-2 cells)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | VE822; VE 822 |
Observed_band | 463.55 |
Notes | VE-822 is a selective ATR inhibitor with an Ki value of 0.2 nM, >150 fold selectivity over ATM (Ki=34 nM), DNA-PK (Ki >4 uM) and mTOR (Ki >1 uM). Ki: <0.2 nM (ATR), 34 nM (ATM)[1] IC50: 19 nM (ATR, in PSN-1 and MiaPaCa-2 cells), 2.6 μM (ATM, in PSN-1 |
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