抑制剂与激动剂

Catalog_noADMC0671
Product_nameAnacetrapib(MK0859)
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price2220.00/6440.00/10880.00
SpecificityTarget: CETP. Fields: Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.
DilutionIC50: 7.9±2.5 nM (rhCETP), 11.8±1.9 nM (CETPC13S)[1]
Purification>98%
Concentration靶点:CETP;IC50: 7.9±2.5 nM (rhCETP), 11.8±1.9 nM (CETPC13S)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameMK-0859, MK 0859, MK0859
Observed_band637.51
NotesAnacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.
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