400-921-8278
| Catalog_no | ADMC0709 |
| Product_name | PF06463922(Lorlatinib) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1000.00/2660.00/4660.00 |
| Specificity | Target: ALK. Fields: PF06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Ki: < 0.02 nM (ROS1), < 0.07 nM |
| Dilution | Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK L1196M) |
| Purification | >99% |
| Concentration | 靶点：ALK;IC50：Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK L1196M) |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | PF06463922,PF-06463922,PF 06463922 |
| Observed_band | 406.1 |
| Notes | PF06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Ki: < 0.02 nM (ROS1), < 0.07 nM (ALK WT), 0.7 nM (ALK |
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