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| Catalog_no | ADMC0875 |
| Product_name | Entrectinib (RXDX-101) |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1340.00/5000.00/8220.00 |
| Specificity | Target: ALK. Fields: Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. IC50: 1 nM (Tr |
| Dilution | IC50: 1 nM (TrkA), 1 nM (TrkB), 1 nM (TrkC), 1 nM (ROS1),1 nM (ALK)[1] |
| Purification | >98% |
| Concentration | 靶点：ALK;IC50： 1 nM (TrkA), 1 nM (TrkB), 1 nM (TrkC), 1 nM (ROS1),1 nM (ALK)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | NMS E628; RXDX-101,NMSE628; RXDX 101,NMS-E628; RXDX101 |
| Observed_band | 560.64 |
| Notes | Entrectinib (RXDX-101), a potent and selective small molecule inhibitor of TrkA/B/C, ROS1, and ALK kinases, has demonstrated early clinical activity when orally administered intermittently under fasting conditions. IC50: 1 nM (TrkA), 1 nM (TrkB), 1 n |
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