400-921-8278
| Catalog_no | ADMC0928 |
| Product_name | BI-847325 |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 2000.00/7000.00/9780.00 |
| Specificity | Target: MEK. Fields: BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respec |
| Dilution | IC50: 25 nM (hAK-A), 15 nM (hAK-C), 25 nM (MEK1), 4 nM (MEK2)[1] |
| Purification | >98% |
| Concentration | 靶点：MEK;IC50： 25 nM (hAK-A), 15 nM (hAK-C), 25 nM (MEK1), 4 nM (MEK2)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | BI-847325,BI 847325,BI847325 |
| Observed_band | 464.56 |
| Notes | BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1. |
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