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Catalog_no | ADMC0954 |
Product_name | MK-2461 |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 3880.00/13340.00/24000.00 |
Specificity | TargetTargetTargets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. |
Purification | >98% |
Concentration | 靶点:c-Met/HGFR;IC50:No data |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | MK-2461,MK2461,MK 2461 |
Observed_band | 495.55 |
Notes | MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. |
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