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Catalog_no | ADMC1005 |
Product_name | CO-1686 hydrobromide |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 880.00/1840.00/2840.00 |
Specificity | TargetTargets the mutant forms of EGFR including T790M (IC50=21 nM). |
Dilution | IC50: 21.5 nM (EGFRL858R/T790M), 303.3 nM (EGFRWT) |
Purification | >98% |
Concentration | 靶点:EGFR;IC50: 21.5 nM (EGFRL858R/T790M), 303.3 nM (EGFRWT) |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | Rociletinib hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide |
Observed_band | 636.46 |
Notes | CO-1686 hydrobromide is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M (IC50=21 nM). |
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