抑制剂与激动剂

Catalog_noADMC1042
Product_nameARS-853
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price12220.00/48880.00/88000.00
SpecificityTarget: Ras. Fields: ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. IC50: 2.5 μM (KRASG12C)[1]
DilutionIC50: 2.5 μM (KRASG12C)[1]
Purification>98%
Concentration靶点:Ras;IC50: 2.5 μM (KRASG12C)[1]
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameARS853,ARS 853
Observed_band432.94
NotesARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. IC50: 2.5 μM (KRASG12C)[1]
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