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Catalog_no | ADMC1042 |
Product_name | ARS-853 |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 12220.00/48880.00/88000.00 |
Specificity | Target: Ras. Fields: ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. IC50: 2.5 μM (KRASG12C)[1] |
Dilution | IC50: 2.5 μM (KRASG12C)[1] |
Purification | >98% |
Concentration | 靶点:Ras;IC50: 2.5 μM (KRASG12C)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | ARS853,ARS 853 |
Observed_band | 432.94 |
Notes | ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation. IC50: 2.5 μM (KRASG12C)[1] |
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