抑制剂与激动剂

Catalog_noADMC1081
Product_nameNSC59984
Category抑制剂与激动剂
Size10mg/50mg/100mg
Price2220.00/8880.00/15560.00
SpecificityTarget: MDM-2/p53. Fields: NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null H
Dilution
Purification>98%
Concentration靶点:MDM-2/p53;IC50:No data
Storage_stability2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
othernameNSC-59984,NSC 59984
Observed_band265.27
NotesNSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null HCT116 cells.
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