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| Catalog_no | ADMC1117 |
| Product_name | Deguelin |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1120.00/3880.00/7000.00 |
| Specificity | TargetTarget p-STAT-3 and c-Myc expression in a dose dependent manner[1]. Deguelin down-regulates Akt signaling probably by disrupting its association with Hsp 90 in cultured HNSCC cells. Deguelin deguelin disrupts the association between Hsp 90 with |
| Dilution | Deguelin (0-500 nM) in a dose and time dependent manner inhibits the growth of MDA-MB-231, MDA-MB-468, BT-549 and BT-20 cells. Deguelin at all concentrations fails to reduce cell numbers in the presence of 1 ng EGF but in the presence of EGF 20 ng re |
| Purification | >98% |
| Concentration | 靶点：akt;IC50：Deguelin (0-500 nM) in a dose and time dependent manner inhibits the growth of MDA-MB-231, MDA-MB-468, BT-549 and BT-20 cells. Deguelin at all concentrations fails to reduce cell numbers in the presence of 1 ng EGF but in the presence of |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | (-)-Deguelin;(-)-cis-Deguelin |
| Observed_band | 394.4172 |
| Notes | Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt. Deguelin (0-500 nM) in a dose and time dependent manner inhibits the growth of MDA- |
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