400-921-8278
| Catalog_no | ADMC1126 |
| Product_name | Niraparib(MK-4827) tosylate |
| Category | 抑制剂与激动剂 |
| Size | 10mg/50mg/100mg |
| Price | 1660.00/4440.00/7220.00 |
| Specificity | Target: PARP. Fields: MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1. |
| Dilution | IC50: 3.8 nM (PARP1), 2.1 nM (PARP2)[1] |
| Purification | >98% |
| Concentration | 靶点：PARP;IC50： 3.8 nM (PARP1), 2.1 nM (PARP2)[1] |
| Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
| othername | Niraparib tosylate;MK 4827 tosylate;MK4827 tosylate |
| Observed_band | 492.5899 |
| Notes | MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1. |
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