400-921-8278
Catalog_no | ADMC1204 |
Product_name | LEE011 succinate |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 780.00/1340.00/2000.00 |
Specificity | TargetTargeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1] |
Dilution | IC50: 10/39 nM (CDK4/6)[1] |
Purification | >98% |
Concentration | 靶点:CDK;IC50: 10/39 nM (CDK4/6)[1] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | Ribociclib; LEE 011; LEE-011 |
Observed_band | 552.63 |
Notes | LEE011 succinate is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. IC50: 10/39 nM (CDK4/6)[1] |
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