400-921-8278
Catalog_no | ADMC1216 |
Product_name | Nazartinib(EGF816) |
Category | 抑制剂与激动剂 |
Size | 10mg/50mg/100mg |
Price | 5560.00/16660.00/23340.00 |
Specificity | Target: EGFR. Fields: Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. Ki: 31 nM (EGFR(L858R/790M) mutant)[2] |
Dilution | Ki: 31 nM (EGFR(L858R/790M) mutant)[2] |
Purification | >98% |
Concentration | 靶点:EGFR;IC50:Ki: 31 nM (EGFR(L858R/790M) mutant)[2] |
Storage_stability | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
othername | EGF-816,EGF 816 |
Observed_band | 495.02 |
Notes | Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. Ki: 31 nM (EGFR(L858R/790M) mutant)[2] |
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