Catalog_no | BD-PD400004 |
Product_name | SARS-CoV/SARS-CoV-2 Nucleocapsid Antibody, Mouse MAb |
Category | 冠状病毒产品 |
Applications | WB,ELISA |
Size | 50μL/100μL |
Price | 2260.00/3760.00 |
immunogen | Recombinant SARS-CoV Nucleoprotein / NP Protein |
Specificity | SARS CoV NucleocapsidHas cross-reactivity in ELISA and WB with SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP Protein |
Source | Recombinant SARS-CoV Nucleoprotein / NP Protein |
Dilution | WB:1:1000-1:5000ELISA:1:5000-1:10000 |
Purification | Protein A |
稀释液/缓冲液 | 0.2 μm filtered solution in PBS |
运输及保存条件 | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Notes | (Antibody |
偶联物 | Unconjugated |
状态 | Liquid |
Instructions |
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