| Catalog_no | AT7269 |
| Product_name | SPTN2 rabbit pAb |
| Category | 抗原抗体 |
| Applications | WB |
| Reactivity | Human,Rat |
| Size | 100μg/50μg/20μg |
| Price | 2000.00/1100.00/500.00 |
| Gene_name | SPTBN2 KIAA0302 SCA5 |
| Protein_name | SPTN2 |
| Human swiss prot no | 6712 |
| Human swiss prot no | O15020 |
| Rat gene id | 29211 |
| Rat swiss prot no | Q9QWN8 |
| immunogen | Synthesized peptide derived from human SPTN2 |
| Specificity | This antibody detects endogenous levels of SPTN2 at Human/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage_stability | -20°C/1 year |
| Background | Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009], |
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