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| Catalog_no | BD-PD400088 |
| Product_name | Anti-Human SARS Coronavirus Nucleoprotein / NP Magnetic Beads Immunoprecipitation (IP) Kit |
| Category | 冠状病毒产品 |
| Applications | Immunoprecipitation (IP), Minimum Protein Purification |
| Size | 20T/100T |
| Price | 2860.00/9300.00 |
| immunogen | Recombinant SARS-CoV Nucleoprotein / NP Protein |
| Specificity | Human SARS Coronavirus Nucleoprotein / NP |
| Background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
| 预测N端 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SARS Coronavirus Nucleoprotein / NP (Catalog#40143-V08B; NP_828858.1; Met1-Ala422). |
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